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22/12/2022 ---- 26/12/2022

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26.12.2022
THEME: ENVIRONMENT

The US faced over Christmas the most powerful winter storm in the last century

In the last few days, record-low temperatures have been registered in large territories of Canada and the US. A powerful and prolonged winter storm brought strong winds and snow in incredible amounts. The scope of the storm has been unprecedented, stretching from Canada as far south as the Rio Grande. The snowfall and blizzard conditions made roads impassable, froze power substations and left more than a dozen dead. At least 38 deaths have now been linked to this severe Arctic freeze. Storm-related deaths were reported in Vermont, Ohio, Missouri, Wisconsin, Kansas, and Colorado. South Florida's temperatures dropped so low that iguanas froze and fell from trees. Over 200'000 people were left without power, with their homes covered in snow and ice. Thousands of flights have been cancelled, preventing many people from reaching their families at Christmas. The western US state of Montana is the worst hit by the cold, with temperatures dropping to -45C. Atlanta and Tallahassee, Florida, were forecast to have their coldest temperature recorded on December 24. Such an event is so rare that it should happen once in a hundred years. However, it is not the first potent and extreme weather event this year. The whole northern hemisphere was hit earlier in the summer by record-high temperatures and droughts. Recently, studies published by eminent climatologists demonstrated that the effects of global warming are to increase the frequency of extreme events. May this recent storm also be a consequence of climate change?

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23.12.2022
THEME: HEALTH

FDA approved the first monoclonal antibody drug for the treatment of COVID-19 hospitalized patients

The FDA has approved Tocilizumab - also known as Actemra and commercialized by Roche Genentech - for treating hospitalized COVID-19 patients. The treatment is for individuals who receive corticosteroids and require supplemental oxygen, non-invasive or invasive mechanical ventilation or oxygenation. Tocilizumab is the first FDA-approved monoclonal antibody treatment for COVID-19, recommended for use as a single intravenous injection. Scientists evaluated Tocilizumab for the treatment of COVID-19 in 4 studies in more than 5500 individuals who were hospitalized. The studies showed that Tocilizumab may improve outcomes in individuals receiving corticosteroids and requiring supplemental oxygen or breathing support. There were no new warnings or precautions related to Tocilizumab noted in the trials, with the most common adverse events being anxiety, constipation, diarrhoea, hypertension, insomnia, nausea, and urinary tract infection. More than one million people hospitalized with COVID-19 have been treated with Actemra worldwide since the pandemic's beginning. Tocilizumab has been approved for use for COVID-19 in the United States, European Union, Japan, the United Kingdom, New Zealand, Russia, and Brazil. It is also provisionally approved in Australia and authorized for emergency use in Ghana, Mexico, and Korea for individuals hospitalized with severe or critical COVID-19. The World Health Organization has also recommended and prequalified the drug.

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