NUNZIUM

News That Matters

08/11/2022 ---- 12/11/2022

A new study led by Prof. Courtine and Dr. Jocelyne Bloch demonstrates which neurons, if activated and remodeled by electrical stimulation, allow chronic patients paralyzed by spinal injuries to stand up, walk and rebuild their muscles. The study was published on November 9 in Nature, involving scientists at the Swiss Federal Institute of Technology (EPFL), the University Hospital of Lausanne (CHUV), and the State University in Lausanne (UNIL), Switzerland. In a multi-year research program patients paralyzed by a spinal cord injury and undergoing electrical stimulation of the area that controls leg movement were able to regain some motor function. The improved motor function was shown in nine patients to last after the electrical stimulation was turned off. This suggested that the nerve fibers used for walking had reorganized. To achieve this result, the scientists relied on the understanding of how neuronal reorganization occurs. The researchers first studied the mechanisms in mice, discovering a surprising property in a family of neurons expressing a specific gene (the Vsx2 gene): while these neurons aren’t necessary for walking, they are essential for the recovery of motor function after spinal cord injury. “It is essential for neuroscientists to understand the specific role that each neuronal subpopulation plays in a complex activity like walking,” says Jocelyne Bloch. “Our new study, in which nine clinical-trial patients were able to recover some degree of motor function thanks to our implants, is giving us valuable insight into the reorganization process for spinal cord neurons.” This advancement, demonstrated in nine subjects, marks a fundamental clinical breakthrough toward the improvement of the quality of life for paralyzed patients. Hopefully, healing the paralytics may become one of the many miracles of science in a not too far future.

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Negotiators from nearly 200 countries will prod each other at COP27 in Sharm el-Sheikh (Egypt) to raise their clean energy ambitions until November 18. Universal access to clean water is a top priority at the meeting since water scarcity has become a critical concern for many developing countries including Egypt. Despite water poverty, on the outskirts of Cairo, the Egyptian government is building a giant belt of lakes and parks deep in the desert called “Green Rivers”. Also referred to as Capital Park, Green Rivers is set to be a river-like series of large-scale urban parks. When finished, it should span over 35 kilometers and cover a total area of 6,200 acres making it six times the size of Central Park in New York City. The artificial body of water is meant to mimic the Nile and become a key piece of the New Capital project, a large-scale project of a new capital city in Cairo. The giant system of lakes, canals, and gardens connecting the New Capital’s different neighborhoods is designed to be 35 kilometers long and encompass what Egypt says will be the largest park in the world. Costs for the first phase were estimated at $500 million, state media reported in 2019. The project also includes two giant manmade lakes, the first of which has been built, according to state media. The video shown off five years ago by Egypt’s prime minister depicts lush riverbanks dotted with trees and occupying vast landscapes of greenery – even though the site is in the middle of a desert, with no natural sources of water nearby. Just how the government plans to source vast amounts of water for the project is still unclear. The park is being constructed in the middle of a worsening climate crisis where water scarcity is one of the main issues. In May, the Minister of Local Development announced that the country had entered a stage of “water poverty” according to UN standards. The UN doesn’t have a metric for “water poverty,” but by its definition, a country is considered water scarce when annual supplies drop below 1,000 cubic meters per capita. Egypt needs an estimated 114 billion cubic meters of water per year. Furthermore, as record high temperatures have been registered around the globe, Egypt may also face heatwaves in the next future which would make things even more challenging. This said, the world certainly looks forward to seeing Egypt’s New Capital in all its splendor.

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The US midterm elections of 2022 are arguably the most discussed and awaited. They come at a historical time for America and the world. The US economy is indeed facing high inflation, while tensions are high with Russia over the Ukraine crisis and China over Taiwan. Furthermore, internal politics is in turmoil due to a succession of facts involving former president Donald Trump. On January 6, 2021, following then–U.S. President Donald Trump's defeat in the 2020 presidential election, a mob of his supporters attacked the Capitol Building in Washington, D.C. They sought to keep Trump in power by preventing a joint session of Congress from counting the electoral college votes to formalize the victory of President-elect Joe Biden. An ongoing investigation is now assessing the possibility that this was premeditated by Trump with the intent to overturn the election results. After Biden is elected president, however, other events occurred that put Trump under scrutiny. After a long procedure involving the National Archives and the FBI, on August 8 2022 the FBI executed a search warrant at Trump's Florida property, uncovering 13 boxes or containers with documents marked classified. Trump, in a post online, says the records were "all declassified" and placed in "secure storage." A day later, Trump, who continues to hint at a possible 2024 run for the presidency, cites the FBI search in a campaign fundraising appeal. A legal process is now ongoing to assess the penal responsibilities of ex-president Trump, who has been pushing the electoral campaigns for the Republicans. After the vote on November 8 Republicans are favored to win the House of Representatives, but the fight for the Senate is on a knife edge. Although President Joe Biden is not on the ballot, the midterms will shape the fate of his agenda. If Democrats lose control of either the House or the Senate their decisional power will be more limited than in the last two years. Until now, president Joe Biden could count on a strong majority in the House while the Senate, in parity, was to be considered a majority since Vice President Kamala Harris holds the casting vote power. Despite the results having been beyond the expectations of the Democrats, which feared a “red wave” in favor of the Republicans, it remains true that they will not have a strong majority in either of the two chambers, therefore ensuring hardships ahead for current president Joe Biden.

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