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14/10/2022 ---- 19/10/2022

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19.10.2022
THEME: HEALTH

A new DNA-based screening test has been developed to predict cervical, ovarian, and breast cancer

So far, cervical cancer screening has been the most successful personalized cancer prevention strategy. This type of screening aims to identify women with a pre-invasive lesion, which can be then surgically excised. Infection with human papillomavirus (HPV, which is sexually transmitted) could increase the risk of cancer of the cervix, vulva, and vagina. Today, many countries are adopting screening for human papillomavirus (HPV) as the primary investigation for cervical cancer. The test consists of the cytological analysis of a small biopsy of the cervix: high-risk HPV-positive women are identified and successive eventual treatment is determined. However, many patients are developing this type of cancer that are HPV-negative, implying that preventive diagnosis remains limited to a minority of cases. Scientists from the University of Innsbruck and University College London (UCL) developed a new screening test based on a DNA analysis that brings preventive diagnosis significantly beyond. The study, published in Genome Medicine, demonstrates a DNA methylation test of the cervical fluid capable of identifying women with a high risk of developing cervical, ovarian, and breast cancer. Such methodology opens the way to the more efficient and quick prediction of multiple cancer risks - and therefore a concrete possibility to a systematic early cancer diagnosis, the most important factor for increased chances of success in successive treatment.

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17.10.2022
THEME: ENVIRONMENT

Devastating floods in Nigeria kill more than 500 people and displace Millions

On October 14 devastating floods caused by heavier-than-usual rain hit Nigeria. More than 500 people were killed and roughly 90.000 homes are underwater as well as food and fuel supplies are blocked. The floods have impacted 1.4 million people which are currently displaced. According to the humanitarian ministry, flooding this year was similar to Nigeria’s last major flooding in 2012, which killed 363 people and displaced 600.000 people. The World Food Programme indicates that Nigeria is at risk of poverty and vulnerable to food shortage, often caused by periodic floods that put the agriculture sector under pressure. The abnormal floods in Nigeria this year are just one of the many recent signs of climate change: indeed, in the last months, we witnessed natural extreme events around the world. In September severe floods hit Italy, Japan, Puerto Rico and the Dominican Republic, and Pakistan. Earlier than that, in August, extreme temperatures occurred in the US, China, and central EU - where serious drought put at risk harvests and drinking water availability. Such a high frequency of events due to extreme climate demonstrates not only that climate change is happening, but in some cases that it can turn into a real humanitarian catastrophe.

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15.10.2022
THEME: TECHNOLOGY

Neurons cultured on silicon arrays and exposed to electrical feedback learned to play game Pong

The neurons are the cells responsible for receiving input from the external world and for sending motor commands to muscles. In a recent study published by a team of scientists from Monash University, Melbourne (Australia) and UC London (UK) 800’000 neurons cultured on silicon in a petri dish have learned to play the arcade 1970’s arcade game pong. Through silicon chips and arrayed electrodes, the scientists have connected humans and murine neurons to a computer where they were made aware when the paddle was making contact with the ball. It has been monitored the activity and responses of the neurons and plotted the results as spikes on a grid with spikes getting stronger the more a neuron moves a paddle and hit the ball. The results published in the journal Neuron demonstrated that neurons can adapt the activity to a changing environment in real-time. These findings pave the way to a better understanding of how intelligence arises, which would help to develop new algorithms for machine learning. Harnessing the computational power of living neurons to create synthetic biological intelligence (SBI), previously confined to the realm of science fiction, may now be within reach of human innovation.

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