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28/09/2022 ---- 29/09/2022

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29.09.2022
THEME: HEALTH

Historic moment for Alzheimer's treatment: an experimental drug demonstrated slowing the disease’s progression

On Wednesday the experimental drug “lecanemab”, developed by Eisai (Japan) and Biogen (USA), has been declared efficient as a result of a large phase 3 clinical study involving 1795 patients with early Alzheimer’s disease. With high statistical significance, lecanemab has shown a reduction in clinical decline in patients. It has been shown that the drug slowed the progress of the disease by 27% compared to the placebo. Toxic plaques made of “amyloid-beta” proteins are considered the probable cause of Alzheimer’s disease. The drug reduced the number of toxic plaques in the brain and slowed the decline in memory and ability to perform daily tasks. Lecanemab has been the first one able to successfully slow cognitive decline in Alzheimer’s patients. This is a great achievement for science and medicine, which now offer hope for patients and their families desperate for effective treatment. The multinational pharmacology company Roche, together with Genentech and the Swiss laboratory AC Immune is developing a second drug based on the same principle, which hopefully will even reinforce future treatments.

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28.09.2022
THEME: WORLD

Russia claims 15% of Ukraine territory through questioned Referenda while tensions escalate internally and abroad

On September 20 the Russian-installed leaders of four regions of southern and eastern Ukraine - Kherson, Zaporizhzhia, Luhansk, and Donetsk - called for referendums to join Russia. Today the first results have been released: with no surprise, a large majority was declared in favor of annexation to Russia. It means around 15% of Ukrainian territory - an area about the size of Hungary or Portugal - is now under the direct control of the Kremlin. From today the Kremlin’s narrative may switch to claim Russia itself is under attack from NATO weapons: this justified several threats to the use of nuclear weapons in the last few days as well as the mobilization of hundreds of thousands of Russian troops. The international reactions are mixed in the level of condemnation of the process, but almost every state (including China and India) are asking to stop the war as soon as possible. Russian state media claim that the vote has been regular and that observers from all over the world (including France and Germany) reported no violations. However, western media noted that the process has been breaching the United Nations Principles for international observation: first of all an international election observer mission must respect the “sovereignty of the country holding elections,” and the host country – in this case, Ukraine – should invite international observers. US and NATO members already condemned the vote before the results were known. NATO chief Jens Stoltenberg said in a tweet that he spoke with Ukrainian President Volodymyr Zelenskyy and told him that the military alliance is "unwavering" in its support for Ukraine's sovereignty and right to self-defense. As previously stated, Kyiv is likely to continue in the pursuit of its military goals - which include the “liberation of Ukraine until Crimea”. After Putin announced mobilization last week, long queues have been reported at the frontiers with Georgia, Finland, and Kazakhstan, where men were questioned about their military eligibility before being allowed through. Spontaneous manifestations have flared across Russia and continue in a wave of protests involving thousands - despite penalties for those fleeing a mandatory military call-up by up to 10 years of jail since Saturday. In the meantime, two leaks on the Russian-owned Nord Stream 1 pipeline in Swedish and Danish waters, shortly after a leak on the nearby Nord Stream 2 project, were discovered. Ukrainian presidential adviser Mykhaylo Podolyak said the damage to Nord Stream 1 and 2 was "an act of aggression" towards the EU. He added that Russia wanted to cause pre-winter panic and urged the EU to increase military support for Ukraine.

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