NUNZIUM

News That Matters

08/09/2022 ---- 15/09/2022

Whereas women can choose between many methods of contraception, so far the choice for men is reduced to condom or vasectomy - which implies permanent infertility. To overcome this barrier, scientist at the University of Minnesota developed a male pill soon to be tested in a human clinical trial. So far, the data showed that the pill is 99 per cent effective in mice without causing adverse effects. Another option is coming from the University of Edinburgh, where a team developed a shoulder gel releasing the hormone progestin, able to block testosterone production and therefore reducing sperm production. The gel is being evaluated in Phase 2 clinical trials in US. Getting these new options to the market will take between 5 and 10 years mainly because the trials must not only demonstrate the efficacy of the product in preventing the pregnancies, but also the reversibility of the effect - meaning that the couples must manage to conceive once they decide to stop the treatment. With female rights debate on the rise, especially after the decision of the US Supreme Court about the right of abortion (June 24) and the anti-abortion laws passed in Hungary (September 15), male contraceptives may slowly become important to political and societal debates.

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Currently up to 21985 cases of monkeypox have been confirmed in the US and 23000 cases in Europe. Although monkeypox is rarely fatal, people with a weak immune system are more likely to get seriously ill or die. It was the case for a Los Angeles resident who died last Monday after being hospitalised. It is the second fatal case monkeypox certificated in the US since May 2022. On September 13, in occasion of the 72nd session of the WHO Regional Committee for Europe, the Commissioner for Health and Food Safety and WHO Regional Director for Europe declared that the virus, previously only linked to person-person spread in non-endemic countries, now represents a public health emergency of international concern. EU and WHO reconfirmed their joint efforts to prevent monkeypox from becoming endemic in Europe and better protect the citizens.

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On September 12 Ukraine president Volodymyr Zelenskyy said that "since the beginning of September our soldiers have already liberated 6,000 square kilometres of Ukrainian territory in the east and south, and we are continuing to advance". It is yet not clear if this counteroffensive could be the tipping point of the war. However, it is confirmed also from Russian sources that Kremlin’s troops have lost key cities in the north-eastern Kharkiv region and are under pressure in other key locations in the South. To date Russia still holds one fifth of the country and maintains troops and munitions in Ukrainian territory. Eastern media argue that this will lead to a prolonged conflict. In the meantime in Russia the sentiment that the “special military operation” was a mistake is mounting: dozens of municipal deputies from Moscow and St. Petersburg have called on President Vladimir Putin to resign in an open letter published Monday, despite the signatories being now at risk of severe punishment. “President Putin's actions are detrimental to the future of Russia and its citizens” reads the petition. Even more notable, such criticism seeped onto state-controlled Russian TV. “People who convinced President Putin that the operation will be fast and effective ... these people really set up all of us,” Boris Nadezhdin, a former parliament member, said on a talk show on NTV television. “We're now at the point where we have to understand that it's absolutely impossible to defeat Ukraine using these resources and colonial war methods.” Despite this criticism the Kremlin continues to state that the objectives of the special military operations will be achieved as Russia’s forces are now being reinforced.

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The Paris Agreement is a legally binding international treaty on climate change. It was adopted by 196 Parties at COP 21 in Paris, on 12 December 2015 and entered into force on 4 November 2016. Its goal is to limit global warming to well below 2, preferably to 1.5 degrees Celsius, compared to pre-industrial levels. A study published on September 8 on Science highlights the importance of such objectives: by reviewing historic records and more than 200 peer-reviewed works, scientists determined that multiple climate tipping points could be triggered if global temperature rises beyond 1.5°C above pre-industrial levels. By “tipping point” is meant the minimum amount of warming that might trigger a catastrophic shift in a system. The team found that at the current level of global warming - 1.1°C since the preindustrial era - Earth has already passed the low-end risk estimate for five tipping points, putting coral reefs, permafrost, and polar ice at risk. For polar ice sheets, however, the authors estimate that 1.5°C is the more likely tipping threshold, and that the sheets might be able to withstand as much as 3°C of warming without irreversible decline. Despite the study also indicates that a lot of really bad tipping points are still avoidable, lead author David Armstrong McKay from Stockholm Resilience Centre, University of Exeter, and the Earth Commission says that “the chance of crossing tipping points can be reduced by rapidly cutting greenhouse gas emissions, starting immediately”.

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New York Governor Kathy Hochul declared a disaster emergency on Friday in a bid to accelerate efforts to vaccinate residents against polio after the virus was detected in wastewater samples taken in four counties. In early August a health official in New York State had already announced that there could be hundreds or even thousands of undiagnosed cases of polio. The vaccination is the only weapon against this virus. In the state of New York polio vaccination rate is only 79% - some counties having even lower rates. The position of the World Health organisation is clear and states that "All children worldwide should be fully vaccinated against polio, and every country should seek to achieve and maintain high levels of coverage with polio vaccines in support of the global commitment to eradicate polio." In some areas of US the access to health care and therefore vaccination are limited due to the high cost of health insurance.

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Yesterday the European Central Bank raised three key interest rates by 75 basis points each: such drastic measure was implemented to fight the high inflation across the continent, mostly due to the ongoing energy crisis. With this premise, today September 9 the energy ministers of EU countries met in Bruxelles to discuss a series of exceptional measures to curb soaring electricity bills. The focus was on five points: (1) introduction of mandatory savings during peak hours, (2) a revenue cap for new producers, (3) capturing excess profits from fossil fuel companies, (4) liquidity aids to utility businesses, (5) a price cap on Russian gas imports. The outcome of this meeting gives to the European Commission a clearer political mandate on how to proceed: there is agreement on necessity to introduce energy saving measures, guarantee liquidity to utility businesses, capping revenues for new producers, and to take a solidarity contribution from fossil fuel companies. The ministers also “expect the Commission to propose emergency and temporary intervention including the gas price cap” said Jozef Síkela - EU minster of Industry and Trade - at the press conference after the meeting. In conclusion, in his words: “When Putin started his energy war he expected to divide us and damage our democratic societies and economies. Hi will not succeed, Europe is united against his aggression”. Concrete legislative proposals on these aspects are expected by the Commission within days.

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In a world where energy crisis and scarcity of natural fossil fuels is more and more problematic, nuclear physics may be once again what separates present and future times. Nuclear fusion promises near-limitless clean energy by mimicking the natural reactions occurring in the Sun. In the past few years several advancements moved fusion towards commercialisation, which may now be only decades away. So far, state-of-the-art magnetic fusion devices could not yet achieve a sustainable fusion performance, which requires a high temperature above 100 million kelvin and sufficient control of instabilities to ensure steady-state operation on the order of tens of seconds. A study published don September 2 in Nature by a team from Seoul National University and the Korea Institute of Fusion Energy - experimented with the reactor at the Korea Superconducting Tokamak Advanced Research (KSTAR) - reported generation of plasmas at a temperature of 100 million kelvin lasting up to 20 seconds without edge instabilities or impurity accumulation. For the first time, a fusion regime rarely subject to disruption and sustained without a sophisticated control is shown. It thus represents a promising path towards commercial fusion reactors. KSTAR is a pilot project that feeds information and technologies into the ITER project. In addition to South Korea, ITER’s 35 member states include China, India, Japan, the EU (including the UK), Russia and the United States. ITER was propelled into force when US President Ronald Reagan and Soviet leader Mikhail Gorbachev met in Geneva in 1985, granting the project with the mandate of benefitting mankind. Multiple countries subsequently joined. In 2005, the international body agreed – after strong bids from Paris and Tokyo – to build ITER in southern France. Construction is underway in Saint Paul-lez-Durance and the ITER facility is expected to come online in December 2025. Experts say that by 2035 most feasibility questions will be answered and by 2050 the commercial sector is likely to use fusion plants.

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Elisabeth was queen of the United Kingdom and 14 other Commonwealth realms from 6 February 1952 until her death on 8 September 2022 at the age of 96. Elizabeth reigned as a constitutional monarch through major political changes such as the Troubles in Northern Ireland, devolution in the United Kingdom, the decolonisation of Africa, and the United Kingdom's accession to the European Communities and withdrawal from the European Union. Elizabeth was the longest-lived and longest-reigning British monarch in history. The Crown passes now to her son and heir Charles in an extremely difficult moment for England and the world. Rest in peace Queen Elisabeth.

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